ZONESUN ZS-AFC9H Monoblock Automatic Vial Filling and Half Stoppering Machine With Laminar Flow Hood For Lyophilized Products
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ZONESUN vial filling and stoppering machine is designed for precise liquid dosing and flexible vial processing in pharmaceutical, biotech, and related industries. Equipped with a servo-driven peristaltic pump, it ensures ±1% accuracy while allowing easy tubing replacement for improved cleanliness. The double-head filling system delivers 2400–3600 BPH and can be customized for higher capacity. It supports both half and full stoppering, making it suitable for lyophilization workflows and integration with crimping machines. Featuring automatic vial feeding, laminar flow protection, GMP-oriented design, and synchronized cam-driven operation, the machine offers efficient, hygienic, and scalable production performance.
Vial Filling and Stoppering Machine Parameter
- Machine Model: ZS-AFC9H
- Voltage: AC 110/220 V 50-60 Hz
- Power: <3000 W/h
- Working Speed: About 40-60 Bottles/min (Depending on filling range)
- Filling Pump: Peristaltic Pump
- Filling Nozzle Quantity: 2
- Filling Range: Customizable
- Filling Accuracy: ±3%
- Package Size: About 610*1900*1270 mm (Laminar Flow Hood) About 2110*1320*2110 mm (Main Machine)
- Package Weight: About 181 kg (Laminar Flow Hood)+908 kg (Main Machine)
*Specifications are for reference only and may vary by your product. Please confirm with us if required.



Details of Vial Filling and Stoppering Machine
01. Touchscreen Control Panel
User-friendly interface of the vial filling and stoppering machine for precise parameter adjustment and real-time process monitoring, improving operational efficiency and control.

02. Bottle Sorting System
Automatically aligns and feeds vials into the filling station of the vial filling and stoppering machine. Customizable to accommodate different vial sizes for flexible production.

03. Integrated Cam-Driven Structure
Synchronized multi-station operation ensures stable performance, higher efficiency, and reduced mechanical complexity within the vial filling and stoppering machine.

04. Peristaltic Pump Filling System
Enables hygienic, contamination-free filling in the vial filling and stoppering machine, as liquid only contacts the tubing—ideal for sterile and sensitive pharmaceutical products.

05. Vibratory Bowl Stopper Sorter
Efficiently orients and feeds stoppers for continuous, automated production with minimal manual intervention in the vial filling and stoppering machine.

06. Laminar Flow Hood
Provides a consistent stream of clean air over critical processing areas of the vial filling and stoppering machine, minimizing contamination risks and supporting aseptic-oriented production standards.

07. Protective Dust Cover
Helps isolate the working area of the vial filling and stoppering machine from external particles, enhancing overall cleanliness and product safety.

FAQ of Vial Filling and Stoppering Machine
1. What is the production capacity of this vial filling and stoppering machine?
The machine is equipped with a dual-head filling system, with a typical output of 2400–3600 bottles per hour. The number of filling heads can be customized to meet higher production requirements.
2. Can this machine be used for lyophilization processes?
Yes. The machine supports both half stoppering and full stoppering modes. Half stoppering is suitable for freeze-drying applications, while full stoppering can be used for direct sealing with a crimping machine.
3. How does the machine ensure filling accuracy?
The system uses a servo-controlled peristaltic pump, achieving filling accuracy of up to ±1%. Accuracy may vary slightly depending on liquid properties and tubing conditions.
4. Is this vial filling and stoppering machine suitable for different vial sizes?
Yes. The machine can accommodate multiple vial sizes by changing format parts such as the star wheel and vibratory bowl. This allows it to handle different bottle dimensions and stopper sizes, providing flexibility for various production requirements.
5. Is the filling system easy to clean and maintain?
Yes. The peristaltic pump uses replaceable tubing, which prevents direct contact between the pump and the liquid, making it easy to clean and suitable for applications requiring higher hygiene standards.
6.Is the machine suitable for sterile or cleanroom environments?
The machine is designed with GMP-oriented structure, SUS304 contact parts, and can be equipped with a laminar flow hood to help minimize contamination risk during filling.