{"product_id":"automatic-vial-filling-and-half-stoppering-machine-for-lyophilized-products","title":"ZONESUN ZS-AFC9H Monoblock Automatic Vial Filling and Half Stoppering Machine With Laminar Flow Hood For Lyophilized Products","description":"\u003cp\u003eZONESUN vial filling and stoppering machine is designed for precise liquid dosing and flexible vial processing in pharmaceutical, biotech, and related industries. Equipped with a servo-driven peristaltic pump, it ensures ±1% accuracy while allowing easy tubing replacement for improved cleanliness. The double-head filling system delivers 2400–3600 BPH and can be customized for higher capacity. It supports both half and full stoppering, making it suitable for lyophilization workflows and integration with crimping machines. Featuring automatic vial feeding, laminar flow protection, GMP-oriented design, and synchronized cam-driven operation, the machine offers efficient, hygienic, and scalable production performance.\u003c\/p\u003e\n\u003ch2\u003e\u003cstrong\u003eVial Filling and Stoppering Machine Parameter\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e\u003c\/strong\u003eMachine Model: ZS-AFC9H\u003c\/li\u003e\n\u003cli\u003eVoltage: AC 110\/220 V 50-60 Hz\u003c\/li\u003e\n\u003cli\u003ePower: \u0026lt;3000 W\/h\u003c\/li\u003e\n\u003cli\u003eWorking Speed: About 40-60 Bottles\/min (Depending on filling range)\u003c\/li\u003e\n\u003cli\u003eFilling Pump: Peristaltic Pump\u003c\/li\u003e\n\u003cli\u003eFilling Nozzle Quantity: 2\u003c\/li\u003e\n\u003cli\u003eFilling Range: Customizable\u003c\/li\u003e\n\u003cli\u003eFilling Accuracy: ±3%\u003c\/li\u003e\n\u003cli\u003ePackage Size: About 610*1900*1270 mm (Laminar Flow Hood) About 2110*1320*2110 mm (Main Machine)\u003c\/li\u003e\n\u003cli\u003ePackage Weight: About 181 kg (Laminar Flow Hood)+908 kg (Main Machine)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003e\u003cstrong\u003e*Specifications are for reference only and may vary by your product. Please confirm with us if required.\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"features of vial filling half stoppering machine\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1538\/6957\/files\/features-of-ZS-AFC9H-automatic-vial-filling-and-rubber-stoppering-machine.jpg?v=1777001303\"\u003e\u003c\/div\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"workflow of automatic vial filling and stoppering machine\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1538\/6957\/files\/application-of-ZS-AFC9H-automatic-vial-filling-and-rubber-stoppering-machine.jpg?v=1777001302\"\u003e\u003c\/div\u003e\n\u003cdiv style=\"text-align: left;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"main component of automatic filling and stoppering machine\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1538\/6957\/files\/components-of-ZS-AFC9H-automatic-vial-filling-and-rubber-stoppering-machine.jpg?v=1777001303\"\u003e\u003c\/div\u003e\n\u003ch2 style=\"text-align: center;\"\u003e\u003cstrong\u003e Details of Vial Filling and Stoppering Machine\u003c\/strong\u003e\u003c\/h2\u003e\n\u003ch3 data-section-id=\"lfgwm6\" data-start=\"96\" data-end=\"131\" style=\"text-align: center;\"\u003e\u003cspan role=\"text\"\u003e\u003cstrong data-start=\"100\" data-end=\"129\"\u003e01. Touchscreen Control Panel\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp data-start=\"132\" data-end=\"315\" style=\"text-align: center;\"\u003eUser-friendly interface of the vial filling and stoppering machine for precise parameter adjustment and real-time process monitoring, improving operational efficiency and control.\u003c\/p\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"control panel of vial filling and stoppering machine\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1538\/6957\/files\/control-panel-of-ZS-AFC9H-automatic-vial-filling-and-half-stoppering-machine.jpg?v=1777001303\"\u003e\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\n\u003ch3 data-section-id=\"v6wggt\" data-start=\"322\" data-end=\"353\"\u003e\u003cspan role=\"text\"\u003e\u003cstrong data-start=\"326\" data-end=\"351\"\u003e02. Bottle Sorting System\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp data-start=\"354\" data-end=\"537\"\u003eAutomatically aligns and feeds vials into the filling station of the vial filling and stoppering machine. Customizable to accommodate different vial sizes for flexible production.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"bottle sorting system of automatic vial packaging machine\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1538\/6957\/files\/bottle-sorting-system-of-ZS-AFC9H-automatic-vial-filling-and-half-stoppering-machine.jpg?v=1777001303\"\u003e\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\n\u003ch3 data-section-id=\"cwa3l0\" data-start=\"544\" data-end=\"585\"\u003e\u003cspan role=\"text\"\u003e\u003cstrong data-start=\"548\" data-end=\"583\"\u003e03. Integrated Cam-Driven Structure\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp data-start=\"586\" data-end=\"751\"\u003eSynchronized multi-station operation ensures stable performance, higher efficiency, and reduced mechanical complexity within the vial filling and stoppering machine.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"integrated cam-driven system of liquid filling and stoppering machine for vial\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1538\/6957\/files\/integrated-working-structure-of-ZS-AFC9H-automatic-vial-filling-and-half-stoppering-machine.jpg?v=1777001303\"\u003e\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\n\u003ch3 data-section-id=\"1sxadce\" data-start=\"758\" data-end=\"799\"\u003e\u003cspan role=\"text\"\u003e\u003cstrong data-start=\"762\" data-end=\"797\"\u003e04. Peristaltic Pump Filling System\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp data-start=\"800\" data-end=\"980\"\u003eEnables hygienic, contamination-free filling in the vial filling and stoppering machine, as liquid only contacts the tubing—ideal for sterile and sensitive pharmaceutical products.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"peristaltic pump filling system of vial filling and capping machine\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1538\/6957\/files\/peristaltic-pump-filling-system-of-ZS-AFC9H-automatic-vial-filling-and-half-stoppering-machine.jpg?v=1777001302\"\u003e\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\n\u003ch3 data-section-id=\"162t6m4\" data-start=\"987\" data-end=\"1026\"\u003e\u003cspan role=\"text\"\u003e\u003cstrong data-start=\"991\" data-end=\"1024\"\u003e05. Vibratory Bowl Stopper Sorter\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp data-start=\"1027\" data-end=\"1179\"\u003eEfficiently orients and feeds stoppers for continuous, automated production with minimal manual intervention in the vial filling and stoppering machine.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"vibratory bowl stopper sorter of vial partial stoppering machine\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1538\/6957\/files\/cap-vibratory-bowl-sorter-of-ZS-AFC9H-automatic-vial-filling-and-half-stoppering-machine.jpg?v=1777001303\"\u003e\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\n\u003ch3 data-section-id=\"ynch4c\" data-start=\"1186\" data-end=\"1213\"\u003e\u003cspan role=\"text\"\u003e\u003cstrong data-start=\"1190\" data-end=\"1211\"\u003e06. Laminar Flow Hood\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp data-start=\"1214\" data-end=\"1415\"\u003eProvides a consistent stream of clean air over critical processing areas of the vial filling and stoppering machine, minimizing contamination risks and supporting aseptic-oriented production standards.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"laminar flow hood of automatic vial packaging machine\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1538\/6957\/files\/laminar-flow-hood-of-ZS-AFC9H-automatic-vial-filling-and-half-stoppering-machine.jpg?v=1777001303\"\u003e\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\n\u003ch3 data-section-id=\"1f5lpn0\" data-start=\"1422\" data-end=\"1453\"\u003e\u003cspan role=\"text\"\u003e\u003cstrong data-start=\"1426\" data-end=\"1451\"\u003e07. Protective Dust Cover\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp data-start=\"1454\" data-end=\"1602\"\u003eHelps isolate the working area of the vial filling and stoppering machine from external particles, enhancing overall cleanliness and product safety.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\n\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"protective dust cover of vial filling and capping machine\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1538\/6957\/files\/dust-cover-of-ZS-AFC9H-automatic-vial-filling-and-half-stoppering-machine.jpg?v=1777001302\"\u003e\u003cspan role=\"text\"\u003e\u003cstrong data-start=\"1426\" data-end=\"1451\"\u003e\u003c\/strong\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cimg style=\"margin-bottom: 16px; float: none;\" alt=\"automatic vial filling half stoppering machine for lyophilized products\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1538\/6957\/files\/ZS-AFC9H-automatic-vial-filling-and-stoppering-machine.jpg?v=1777001303\"\u003e\u003c\/div\u003e\n\u003ch2 style=\"text-align: left;\"\u003eFAQ of Vial Filling and Stoppering Machine\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003e1. What is the production capacity of this vial filling and stoppering machine?\u003c\/strong\u003e\u003cbr\u003eThe machine is equipped with a dual-head filling system, with a typical output of 2400–3600 bottles per hour. The number of filling heads can be customized to meet higher production requirements.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e2. Can this machine be used for lyophilization processes?\u003c\/strong\u003e\u003cbr\u003eYes. The machine supports both half stoppering and full stoppering modes. Half stoppering is suitable for freeze-drying applications, while full stoppering can be used for direct sealing with a crimping machine.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e3. How does the machine ensure filling accuracy?\u003c\/strong\u003e\u003cbr\u003eThe system uses a servo-controlled peristaltic pump, achieving filling accuracy of up to ±1%. Accuracy may vary slightly depending on liquid properties and tubing conditions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e4. Is this vial filling and stoppering machine suitable for different vial sizes?\u003c\/strong\u003e\u003cbr\u003eYes. The machine can accommodate multiple vial sizes by changing format parts such as the star wheel and vibratory bowl. This allows it to handle different bottle dimensions and stopper sizes, providing flexibility for various production requirements.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e5. Is the filling system easy to clean and maintain?\u003c\/strong\u003e\u003cbr\u003eYes. The peristaltic pump uses replaceable tubing, which prevents direct contact between the pump and the liquid, making it easy to clean and suitable for applications requiring higher hygiene standards.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e6.Is the machine suitable for sterile or cleanroom environments?\u003c\/strong\u003e\u003cbr\u003eThe machine is designed with GMP-oriented structure, SUS304 contact parts, and can be equipped with a laminar flow hood to help minimize contamination risk during filling.\u003c\/p\u003e","brand":"ZONESUN","offers":[{"title":"ZS-AFC9H \/ 110V","offer_id":48080801988849,"sku":null,"price":25199.0,"currency_code":"USD","in_stock":true},{"title":"ZS-AFC9H \/ 220V","offer_id":48080802021617,"sku":null,"price":25199.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1538\/6957\/files\/ZS-AFC9H-automatic-vial-filling-and-rubber-stoppering-machine.jpg?v=1777001303","url":"https:\/\/www.zonesuntech.com\/products\/automatic-vial-filling-and-half-stoppering-machine-for-lyophilized-products","provider":"ZONESUN Technology Limited | Packing Machine Manufacturer","version":"1.0","type":"link"}